ISAKOS Congress 2021

2021 ISAKOS Biennial Congress Paper

 

Outcomes of Medial Patellofemoral Ligament Reconstruction for Recurrent Patellar Instability in Patients with Ehlers-Danlos Syndrome

James Nemunaitis, DO, Erie, Pennsylvania UNITED STATES
Shital N. Parikh, MD, Cincinnati, OH UNITED STATES

Cincinnati Children's Hospital and Medical Center, Cincinnati, OH, UNITED STATES

FDA Status Not Applicable

Summary

This is a study examining clinical and patient reported outcome measures for patients with Ehlers-Danlos syndrome and patella instability that was treated with Medial Patellofemoral Ligament Reconstruction.

Abstract

Purpose

Ehlers-Danlos syndrome (EDS) -hypermobility type is characterized by generalized hyperlaxity which is considered to be a risk factor for patellar instability. Surgery is discouraged in this subset of patients due to high rates of failure. The outcomes following isolated Medial Patellofemoral Ligament Reconstruction (MPFLR) for patellar instability in EDS population has not been reported.

Methods

Between 2010 and 2016, 21 knees in 16 consecutive patients with EDS underwent isolated MPFLR reconstruction for patellar instability. The diagnosis of EDS-hypermobility type, was confirmed by genetics for all patients, with Beighton score as the chief determinants. All patients were cared for by a multidisciplinary team including genetics, pain management and physical therapy. Recurrent dislocation rate and patient-reported outcomes, including Pedi-IKDC, Kujala Score, HSS Pedi-FABS, Banff Instability Instrument 2.0, and KOOS Knee Survey were collected at minimum 2 year follow-up.

Results

The mean age of the cohort was 15.4 years (range 13-18 years). All patients were females. 16 knees had atraumatic mechanism of patellar dislocation; 4 had traumatic and 2 patients had an osteochondral fracture. 5 patients underwent bilateral MPFLR. 9 patients had prior surgeries on their knee; 6 were failed patellar stabilization procedures but only 1 was failed MPFLR. 14 knees had autograft hamstring and 7 had allograft hamstring MPFLR; there were no differences in outcomes based on graft choice. 7 patients had concomitant surgery during MPFLR; 6 were chondroplasty of patella/lateral femoral condyle. At minimum 2 years follow-up, 3 of 21 knees (14.2%) had recurrent dislocation. There were no other complications. The mean pedi IKDC, Kujala, Pedi-FABS, and BANFF scores were 66.62 (95% CI 8.52), 73.5 (95% CI 8.68), 6.73 (95% CI 2.86) and 57.15 (95% CI 10.24) respectively. The overall mean KOOS pain subscale was 73.85 (95% CI 9.95) and KOOS symptoms subscale score was 48.54 (95% CI 5.56). There were no significant differences in outcome scores and re-dislocation rates between autograft and allograft (p>0.5). There was no significant correlation between functional score and Beighton score.

Conclusion

EDS-related patellar instability are primarily atraumatic in origin without an osteochondral fracture. Patients had significant improvements in function following isolated MPFLR at minimum 2 years follow-up. However, these functional improvements, based on validated patient-reported outcomes, were significantly less than historical controls. Re-dislocation rate of 14% is higher than normal population. EDS and joint hypermobility is not a contraindication to MPFLR but caution is recommended in managing patient expectations.

Significance

This study will influence management and help improve the outcomes for patients with EDS or joint hypermobility and patellar instability.

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