2023 ISAKOS Biennial Congress ePoster
Clinical and Functional Results With A Minimum Follow-Up Of Two Years After Collagen Matrix-Induced Chondrogenesis In Patelofemoral Injuries
José Ricardo Dantas Moura Costa, MD, São Paulo, São Paulo BRAZIL
Nathalia Bofill Burger, Uruguaiana, Rio Grande do Sul BRAZIL
Marcel Henrique Arcuri, Md, Sao Paulo BRAZIL
Diego Costa Astur, MD, PhD, São Paulo, SP BRAZIL
Camila Cohen Kaleka, PhD, São Paulo, SP BRAZIL
Pedro Debieux, MD, PhD, São Paulo, SP BRAZIL
Moises Cohen, MD, PhD, Prof., São Paulo, SP BRAZIL
Hospital Israelita Albert Einstein, São Paulo, São Paulo, SP, BRAZIL
FDA Status Not Applicable
Summary
After follow-up of two years, AMIC is a safe, effective and viable method for the treatment of symptomatic, full-thickness patellofemoral chondral defects.
ePosters will be available shortly before Congress
Abstract
Objective
To evaluate the clinical and functional outcomes in patients undergoing surgical treatment to repair a focal chondral lesion in the patella and trochlea, using the matrix-induced chondrogenesis (MCA) technique, after a minimum of two years of treatment.
Methods
Twenty-four patients (25 knees) who underwent patellofemoral AMIC with a mean age of 39.6 ± 4.7 years were evaluated at a mean follow-up of 3.64 ± 0.65 years. Patient factors, lesion morphology, and patient-reported outcome measures, including IKDC score, Tegner, Kujula, Fulkerson, Lysholm, and visual analogue scale (VAS) score were collected.
Results
Most patients were male (76%). The mean defect size of chondral lesions was 1.99 ± 0.36 cm². All defects were classified as grade IV according to the Outerbridge classification. At the final follow-up, patients had an increase in mean Kujala score from 61.9 to 87.9, IKDC from 51.3 to 83.6, Lysholm from 64.0 to 88.4, Tegner from 4.04 to 5.12, Fulkerson from 60.2 to 89.3 and EVA Scale from 5.6 to 1.24. All results with statistical significance (p-value <0.05).
Conclusion
Injuries to the articular cartilage of the knee still constitute a major challenge for the orthopedic surgeon. In conclusion, AMIC is a safe, effective and viable method for the treatment of symptomatic, full-thickness patellofemoral chondral defects in appropriately selected cases and resulted in clinical and functional improvement and all criteria analyzed.