2023 ISAKOS Biennial Congress ePoster
Use of Fresh Frozen Osteochondral Allograft for the Treatment of Cartilage Defects of the Knee Functional Results And Failure Rate at a Mean Seven-Year Follow-Up
Pablo Dardanelli, MD, Buenos Aires ARGENTINA
Nicolas Molho, MD, Buenos Aires ARGENTINA
Catalina Larrague, MD, Buenos Aires ARGENTINA
Juan Pablo Zicaro, MD, Olivos, Buenos Aires ARGENTINA
Carlos H. Yacuzzi, MD, Buenos Aires, BA ARGENTINA
Matias Costa-Paz, MD, PhD., Buenos Aires, Buenos Aires ARGENTINA
Hospital Italiano de Buenos Aires, Buenos Aires, ARGENTINA
FDA Status Cleared
Summary
Functional results and failure rate at a mean seven-year follow-up of knee osteochondral defects treated with fresh frozen osteochondral allograft.
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Abstract
Introduction
Knee osteochondral lesions represent a frequent pathology within young active patients. One possible indication for severe lesions or in case of impossibility of harvesting an autograft is the use of fresh frozen allograft.
The objective of this study was to retrospectively analyze functional results and failure rate after osteochondral transplants using fresh frozen allografts.
Material And Method
We analyzed data from patients who underwent knee osteochondral transplant using mosaicplasty technique with fresh frozen allografts at our institution between 2014 and 2019. We included those patients with at least two-year follow-up.
Demographic characteristics such as age at the moment of intervention and size of the defect were included. Functional results were assessed using pre and postoperative Lysholm and IKDC scores. Patients who underwent a knee replacement were considered failures.
Results
Twenty-five patients were included. The median age was 43.5 years (IQR 29-50), 45% were female and the mean follow-up was 83 months (SD 54.6). Mean osteochondral defect size was 4cm2. Mean pre and postoperative Lysholm scores were 39 (SD 19.3) and 82 (SD 15.4) respectively (p <0.01). Mean pre and postoperative IKDC scores were 42 (SD 13.8) and 60 (SD 13.5) respectively (p <0.01). Five patients (20%) underwent a knee replacement afterwards and were considered failures.
Conclusion
Our results after a mean seven-years follow-up evidenced an overall improvement in functional scores and a failure rate of 20%. Osteochondral transplant using fresh frozen allgrafts is a reliable and feasible treatment for patients with large osteochondral defects.