2023 ISAKOS Biennial Congress ePoster
Compliance and Outcome of Osteoporosis Treatment After Total Knee Arthroplasty
Yun Seong Choi, MD, Seoul KOREA, REPUBLIC OF
Seung Hoon Lee, MD, Seoul KOREA, REPUBLIC OF
Jung Ro Yoon, MD, Seoul KOREA, REPUBLIC OF
Young Bin Shin, MD, Seoul KOREA, REPUBLIC OF
Tae Hyuk Yoon, MD, Seoul KOREA, REPUBLIC OF
Veterans Health Service Medical Center, Seoul, KOREA, REPUBLIC OF
FDA Status Not Applicable
Summary
Osteoporosis treatment compliance was significantly higher in the total knee arthroplasty group than in the out-patients clinic group and treatment outcome was comparable.
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Abstract
Background
Treatment compliance is important in the treatment of osteoporosis. Our hypotheses were as follows: 1) compliance with osteoporosis treatment after total knee arthroplasty (TKA) will be high, and 2) osteoporosis treatment results after TKA will be as good as those of patients who do not undergo TKA.
Methods
and Materials: Patients diagnosed with osteoporosis for the first time in an outpatient clinic (OPD group) and those who were diagnosed at hospitalization for TKA (TKA group) from March 2019 to December 2020 were retrospectively evaluated. Only patients treated with denoxumab were included in the study. Compliance, based on the outpatient follow-up rate after 1 year, was compared between the two groups, and the treatment outcomes were compared based on bone mineral density (BMD).
Results
In the OPD group, 29 of 41 patients were followed up 1 year later, and in the TKA group, all 26 patients were followed up after 1 year. In the OPD group, the BMD increased significantly. In the TKA group, there was a significant increase in BMD only in the lumbar spine. However, there were no significant between-group differences in the BMD before and after treatment.
Conclusion
Osteoporosis treatment compliance was significantly higher in the TKA group than in the OPD group. When denoxumab was used after TKA, there was no decrease in BMD, and osteoporosis treatment results after TKA were similar to those of the OPD group.