2025 ISAKOS Congress in Munich, Germany

2025 ISAKOS Biennial Congress Paper


Delayed Anterior Cruciate Ligament Reconstruction is Associated with Lower Odds of Returning to Preinjury Physical Activity Level at 12 Months Follow Up

Johan Högberg, PT, MSc, Gothenburg SWEDEN
Emily Fridh, PT, Gnosjö SWEDEN
Ramana Piussi, PhD, Göteborg, Sverige SWEDEN
Rebecca Simonsson, PT, MSc, Västra Frölunda SWEDEN
Riccardo Cristiani, MD, PhD, Stockholm SWEDEN
Kristian Samuelsson, Prof, MD, PhD, MSc, Mölndal, Västra Götalands län SWEDEN
Roland Thomee, Professor, Rönnäng SWEDEN
Eric Hamrin Senorski, PT, PhD, Assoc. Prof., Västra Frölunda SWEDEN

Insitute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, SWEDEN

FDA Status Not Applicable

Summary

Delayed ACL reconstruction reduces the odds of returning to preinjury physical activity level in patients active in pivoting activities preinjury (Tegner 6-10), and in patients regardless of age 12 months after surgery.

Abstract

Purpose

To examine the effects of timing of anterior cruciate ligament (ACL) reconstruction on the odds to recover muscle (quadriceps and hamstring) strength, return to preinjury physical activity level, and achieve rehabilitation goals at 12 months follow-up.

Methods

Data were extracted from a local rehabilitation registry in Sweden in November 2023. Patients ≥16 years old who underwent primary ACL reconstruction with hamstring tendon autografts, who underwent isokinetic muscle strength assessment, and responded to patient-reported outcomes 12-months after surgery were included. A multivariable logistic regression analysis was used to analyze the association between timing of ACL reconstruction and the recovery of muscle strength, return to preinjury physical activity level, and achievement of rehabilitation goals. The results of the logistic regression analysis were expressed as odds ratios (OR) for every 1-unit increase in the predictor variable (months between ACL injury and reconstruction).

Results

In total, 715 patients were included, of which 53.4% (n=383) were women. The mean age at ACL reconstruction was 28.3±10.5 years, and the median time between ACL injury to reconstruction was 4.9 months (IQR 2.9;9.4). Delayed ACL reconstruction significantly decreased the odds of returning to preinjury physical activity level at 12-months in patients with a Tegner score of 6-10 (OR 0.97 [95% CI 0.94;0.99], p=0.009) and regardless of age. Shorter median time in months from ACL injury to reconstruction was observed for patients who returned to preinjury physical activity level, especially in younger patients (16-30 years old) (3.9 [IQR 2.5;6.5] versus 4.7 [IQR 2.9;9.1], p=0.007) and in patients who participated in pivoting activities (Tegner scale 6-10) preinjury (3.4 [IQR 2.3-6.2] versus 5.0 [IQR 2.9-9.7], p<0.001).

Conclusion

Delayed ACL reconstruction reduces the odds of returning to preinjury physical activity level in patients active in pivoting activities preinjury (Tegner 6-10), and in patients regardless of age 12 months after surgery.