Background
Delayed ligamentization following anterior cruciate ligament reconstruction (ACLR) may result in reduced graft stiffness and strength, and an increased risk of secondary re-tear. Remnant sparing ACLR may accelerate ligamentization and proprioceptive function, theoretically reducing re-injury risk.
Hypothesis
A lower graft failure rate and higher perceived functioning knee would exist at 10 years in those undergoing ACLR with remnant preservation (RP), versus remnant debridement (RD).
Study Design: Prospective randomized controlled trial (RCT).
Methods
A prospective RCT allocated 49 patients to ACLR with a hamstrings autograft together with a RD (n=25) or RP (n=24) procedure, of which 86% were clinically evaluated at 10 years (22 RD, 22 RP). A detailed chart review and patient phone consultation was undertaken with all patients at 10 years to evaluate the incidence (and timing) of subsequent re-tear and/or contralateral ACL tear, as well as other knee injuries/surgeries, the patient’s ability to perform full work/sport duties and their perceived knee function using a numerical rating scale (NRS). Independent t-tests were used to compare continuous outcomes, and Chi-square tests (and Fisher’s exact test when appropriate) were used to compare categorical outcomes.
Results
No differences existed between groups (p>0.05) in descriptive variables. There were 2 graft ruptures (10.0%) in the RP group and 3 (13.6%) in the RD group, with an earlier mean time to graft failure in the RD group (RD 7.7 ± 4.5 months, RP 49.5 ± 17.7 months), albeit the size of this sub-sample was too small for statistical comparison. There was a significantly higher number of patients requiring =1 additional ipsilateral knee surgery in the RP group (RP=10, RD=4, p=0.048). At 10 years, 16 (72.7%) and 15 (75.0%) patients in the RD and RP ACLR groups, respectively, were unrestricted in work/sport duties (p=0.867). There were no group differences in the functional NRS ratings (p=0.537).
Conclusions
No long term clinical benefit of RP ACLR could be determined by this study with similar re-tear incidence and perceived knee function, though a higher number of re-operations were observed in RP patients with a tendency toward later time to re-tear. Time to graft rupture may be a useful measure of graft ligamentization
Keywords: anterior cruciate ligament reconstruction, remnant sparing, remnant preservation, clinical outcomes, knee function, re-injury.