2025 ISAKOS Congress in Munich, Germany

2025 ISAKOS Biennial Congress In-Person Poster

 

Role Of Biophysic Stimulation With Pulsed Electromagnetic Fields On Bone Bruise In Anterior Cruciate Ligament Reconstruction

Vito Gaetano Rinaldi, MD, Bologna ITALY
Iacopo Sassoli, MD, Bologna ITALY
Matteo La Verde, MD, Bologna ITALY
Eugenio Cammisa, MD, Bologna, Bo ITALY
Alberto Fogacci, MD, Bologna ITALY
Federico Coliva, MD, Bologna, BO ITALY
Giada Lullini, MD, PhD, Bologna ITALY
Stefano Zaffagnini, MD, Prof., Bologna ITALY
Giulio Maria Marcheggiani Muccioli, MD, PhD, Associate Professor, Bologna ITALY

Rizzoli Orthopaedic Institute, Bologna, Bologna, ITALY

FDA Status Cleared

Summary

Treatment with pulsed electromagnetic fields has proven to be viable in pre- and post-surgery pain management and in improving and accelerating functional recovery, the return to sport, and bone bruise resorption in patients who had undergone ACL reconstruction associated with bone bruise.

Abstract

Introduction

Pulsed electromagnetic fields (iOne®, IGEA S.p.A, Italy) effectiveness in inflammation modulation and articular homeostasis promotion has been widely demonstrated in in-vitro and in-vivo on animal models research.
The primary goal of this study was to evaluate the effectiveness of iOne® in reducing post-operative pain (measured by VAS score) after anterior cruciate ligament (ACL) reconstruction associated with tibial and femoral bone bruise (BB) when applied at least for 4 hours a day, 15 days before and 2 months after surgery.
Secondary goals were quantification of the BB area dimensional reduction (measured by WORMS scale), improvement in knee functional outcomes (measures by IKDC, KOOS and TEGNER scores), and global health condition (measured by SF-12 score).

Methods

Between 2017 and 2022, 66 patients were recruited. Inclusion criteria were: (1) Patients with complete ACL tear associated with BB, (2) aged between 15 and 55 years with (3) MRI acquired within 21 days from trauma. Were excluded from this study patients with (1) previous surgeries on the affected knee, (2) BMI >30, and (3) multi-ligament or cartilage associate lesions.
Patients were randomized into 2 groups (treated with iOne and control group) based on sex, BB > or <1 cm, and smoking habits.
PROMs evaluations were made by VAS, TEGNER, SF-12, KOOS and IKDC scores.

Results

VAS-evaluated pain significantly decreased in pre-surgery (2.76 ± 2.38 – 1.72 ± 2.05, p<0.05) in treated patients.
TEGNER appeared to be significantly greater in pre-surgery (1.43 ± 1.14 – 2.2 ± 1.5, p<0.05) in treated patients.
SF-12 (PCS) appeared to be significantly greater 6 months after surgery (48 ± 9 – 53 ± 5, p<0.05) in treated patients.

Conclusions

Treatment with pulsed electromagnetic fields has proven to be viable in pre- and post-surgery pain management and in improving and accelerating functional recovery, the return to sport, and BB resorption in patients who had undergone ACL reconstruction associated with BB.