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Use of Fresh Frozen Osteochondral Allograft for the Treatment of Cartilage Defects of the Knee Functional Results And Failure Rate at a Mean Seven-Year Follow-Up

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Use of Fresh Frozen Osteochondral Allograft for the Treatment of Cartilage Defects of the Knee Functional Results And Failure Rate at a Mean Seven-Year Follow-Up

Pablo Dardanelli, MD, ARGENTINA Nicolas Molho, MD, ARGENTINA Catalina Larrague, MD, ARGENTINA Juan Pablo Zicaro, MD, ARGENTINA Carlos H. Yacuzzi, MD, ARGENTINA Matias Costa-Paz, MD, PhD, ARGENTINA

Hospital Italiano de Buenos Aires, Buenos Aires, ARGENTINA

2023 Congress ePoster Presentation 2023 Congress Not yet rated

Anatomic Location

Knee

Anatomic Structure

Cartilage

Diagnosis / Condition

Osteoarthritis

Treatment / Technique

Allograft

Cartilage

Cartilage Treatment Cartilage Injuries

Summary: Functional results and failure rate at a mean seven-year follow-up of knee osteochondral defects treated with fresh frozen osteochondral allograft.

Introduction

Knee osteochondral lesions represent a frequent pathology within young active patients. One possible indication for severe lesions or in case of impossibility of harvesting an autograft is the use of fresh frozen allograft.
The objective of this study was to retrospectively analyze functional results and failure rate after osteochondral transplants using fresh frozen allografts.

Material And Method

We analyzed data from patients who underwent knee osteochondral transplant using mosaicplasty technique with fresh frozen allografts at our institution between 2014 and 2019. We included those patients with at least two-year follow-up.
Demographic characteristics such as age at the moment of intervention and size of the defect were included. Functional results were assessed using pre and postoperative Lysholm and IKDC scores. Patients who underwent a knee replacement were considered failures.

Results

Twenty-five patients were included. The median age was 43.5 years (IQR 29-50), 45% were female and the mean follow-up was 83 months (SD 54.6). Mean osteochondral defect size was 4cm2. Mean pre and postoperative Lysholm scores were 39 (SD 19.3) and 82 (SD 15.4) respectively (p <0.01). Mean pre and postoperative IKDC scores were 42 (SD 13.8) and 60 (SD 13.5) respectively (p <0.01). Five patients (20%) underwent a knee replacement afterwards and were considered failures.

Conclusion

Our results after a mean seven-years follow-up evidenced an overall improvement in functional scores and a failure rate of 20%. Osteochondral transplant using fresh frozen allgrafts is a reliable and feasible treatment for patients with large osteochondral defects.

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Use of Fresh Frozen Osteochondral Allograft for the Treatment of Cartilage Defects of the Knee Functional Results And Failure Rate at a Mean Seven-Year Follow-Up

Use of Fresh Frozen Osteochondral Allograft for the Treatment of Cartilage Defects of the Knee Functional Results And Failure Rate at a Mean Seven-Year Follow-Up

Introduction

Material And Method

Results

Conclusion

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Use of Fresh Frozen Osteochondral Allograft for the Treatment of Cartilage Defects of the Knee Functional Results And Failure Rate at a Mean Seven-Year Follow-Up

Use of Fresh Frozen Osteochondral Allograft for the Treatment of Cartilage Defects of the Knee Functional Results And Failure Rate at a Mean Seven-Year Follow-Up

Introduction

Material And Method

Results

Conclusion

More 2023 ISAKOS Congress Content