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Tibial Tubercle-Trochlear Groove (TT-TG) Distance Is Less Predictive Of Patellofemoral Instability Risk Than Three-Dimensional (3D) Trochlear Groove Curvilinearity

Tibial Tubercle-Trochlear Groove (TT-TG) Distance Is Less Predictive Of Patellofemoral Instability Risk Than Three-Dimensional (3D) Trochlear Groove Curvilinearity

Kristin Yu, MD, UNITED STATES Brian Beitler, BS, UNITED STATES John P. Fulkerson, MD, UNITED STATES

Yale School of Medicine, New Haven, CT, UNITED STATES


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Summary: The entry point-transition point angle—a 3D measurement of trochlear groove curvilinearity—demonstrated superior discriminative accuracy between a cohort of patients with recurrent patella instability and age-matched controls over the absolute TT-TG distance and normalized TT-TG/TW ratio.


Background

The tibial tubercle-trochlear groove (TT-TG) distance is a common measurement employed in the evaluation of patella instability patients. The purpose of this study was to evaluate the diagnostic accuracy of the TT-TG distance in differentiating between subjects with recurrent patella dislocation and controls in comparison to a three-dimensional (3D) measurement of trochlear groove curvilinearity, the entry point (EP)-transition point (TP) angle.

Methods

3D prints were generated from patients with a history of recurrent patella dislocation treated by the senior author between January 2020 and November 2021. 24 recurrent patella dislocation patients (18 female, six male) were included. TT-TG distances and trochlear widths were measured on axial CT images. 3D prints were generated from 10 control subjects, all female, with no history of patella dislocation whose whole-body CT scans were included in the New Mexico Decedent Image Database. To evaluate 3D trochlear groove curvilinearity, the entry point (EP)-transition point (TP) angle was used. All EP-TP measurements were obtained with the models resting on their posterior femoral condyles. All statistical analyses were performed in Prism 9.0 using two-way, unpaired student’s t-tests and receiver operating characteristic curves. P-values of <0.05 were considered statistically significant.

Results

No significant differences were observed in TT-TG distance or TT-TG/TW between the recurrent dislocation and control cohorts. Conversely, a significant difference was observed in EP-TP angles between the control and instability cohorts, p<0.0001. More obtuse, larger EP-TP angles were observed in the control subjects. TT-TG and TT-TG/TW area under the curve (AUC) analyses failed to attain statistical significance. An AUC of 0.9250 was observed for EP-TP angle measurements, p<0.0001. The highest likelihood ratio was observed at an EP-TP angle cutoff <144.6 degrees, such that EP-TP angles <144.6 degrees were more 16 times more likely to be observed in control patients than recurrent patella instability patients. This threshold value demonstrated a sensitivity of 80% and specificity of 95% for recurrent patella instability.

Discussion

The EP-TP angle demonstrated superior discriminative accuracy between a cohort of patients with recurrent patella instability and age-matched controls over the absolute TT-TG distance and normalized TT-TG/TW ratio. This three-dimensional measurement of trochlear groove curvilinearity may be incorporated in clinical decision-making for patients with recurrent patella instability.


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