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Acute Postoperative Pain Is An Independent Risk Factor Associated With Chronic Postoperative Pain After Total Knee Arthroplasty

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Acute Postoperative Pain Is An Independent Risk Factor Associated With Chronic Postoperative Pain After Total Knee Arthroplasty

Takuya Iseki, MD, PhD, JAPAN Tomoya Iseki, MD, PhD, JAPAN Yoshitaka Nakao, MD, JAPAN Hiroshi Nakayama, MD., PhD., JAPAN Toshiya Tachibana, MD, PhD, JAPAN

Hyogo Medical University, Nishinomiya , Hyogo, JAPAN

2025 Congress ePoster Presentation 2025 Congress Not yet rated

Anatomic Location

Knee

Treatment / Technique

Arthroplasty

Anatomic Structure

Bones Muscle Nerve

Sports Medicine

Outcome Studies

Summary: Our results indicate that acute postoperative pain after TKA is an independent risk factor for chronic postoperative pain at 1 year postoperatively, and the optimal cut-off value for acute postoperative pain at rest is 37.7 mm of VAS score.

Purpose

The purpose of this study was to examine risk factors for chronic postoperative pain (CPSP) after TKA and to determine whether postoperative acute postoperative pain (APSP) is associated with CPSP.

Methods

A retrospective observational study of patients undergoing unilateral primary total knee arthroplasty (TKA) was conducted at a single university hospital. All patients received the same standardized postoperative pain management and rehabilitation. The 100mm scale visual analogue scale (VAS) score was adopted for the evaluation of the pain scale. For an evaluation of APSP, the VAS score at rest was defined as the mean value measured periodically from the following day to three days after TKA at 6:00 AM, 12:00 PM, and 8:00 PM. For an evaluation of CPSP, the VAS score at rest and during activity were evaluated at 1 year postoperatively, and the presence of CPSP was defined as VAS at rest or during activity of 30 mm or greater.

Results

A total of 263 patients were analyzed and 39 patients (14.8%) were in the CPSP group and 224 patients were in the non-CPSP group. In addition, 51.3% of patients in the CPSP group were dissatisfied compared to 2.6% of patients in the non-CPSP group. The multivariable logistic regression analysis revealed that the APSP at rest was the independent risk factor associated with CPSP (OR = 1.04; 95% CI = 1.01 to 1.08; p = 0.025). The optimal cut-off values of APSP at rest for CPSP were 37.7 (AUC = 0.766, 95% CI = 0.699-0.834).

Conclusion

APSP at rest is an independent risk factor associated with CPSP after TKA and the cut-off value of APSP at rest was a VAS score of 37.7mm.

Knee Arthroplasty ePosters

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Association Between Prosthetic Component Malalignment and Post-Total Knee Arthroplasty Pain ePoster Presentation Luke James Naunton, UNITED KINGDOM Oday Al-Dadah, MBChB, MD, FRCS (Tr & Orth), UNITED KINGDOM
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Functional Alignment Restores Native Kinematics More Consistently than Mechanical Axis Alignment in Total Knee Arthroplasty ePoster Presentation Jonathan R Manara, BMBS, FRCS (Tr & Orth), UNITED KINGDOM Rick Steer, FRACS, AUSTRALIA Sarah L. Whitehouse, PhD, AUSTRALIA Dermot M Collopy, FRACS, AUSTRALIA Gavin William Clark, MBBS, FRACS, AUSTRALIA
Learning Curves in 204 Robotic-Assisted Total Knee Replacements: Comparing Senior, Intermediate, and Senior-Junior Surgical Teams ePoster Presentation Hector Zamorano, MD, CHILE Roberto Yañez, MD,phD,prof, CHILE Sebastian Valdes, student, CHILE Gaston Caracciolo, CHILE Cristobal Yañez, MD, CHILE Sebastian Yanez, MD, CHILE Leonardo Javier Carabajal Vera, MD, ARGENTINA Lars Raymond Strömback, MD, CHILE Magaly Iñiguez, MD, CHILE
Association Between Surgeon Volume And Patient Outcomes After Elective Patellofemoral Joint Replacement Surgery Using Data From The National Joint Registry And Hospital Episode Statistics For England: Population Based Cohort Study ePoster Presentation Martinique Vella-Baldacchino, MD, MRCS, PG CERT (HEALTH LEADERSHIP), IOC DIp Spo, UNITED KINGDOM Alex Bottle, Phd, UNITED KINGDOM Justin Cobb, MCh FRCS, UNITED KINGDOM Alex D Liddle, MBBS BSc DPhil FRCS(Orth), UNITED KINGDOM
The Effects Of The Flexion Gap Setting On Postoperative Outcomes Of Tka Using The Mako Robotic Arm ePoster Presentation Shuhei Sugioka, MD, JAPAN Masayoshi Okuda, MD, PhD, JAPAN Yuki Kawaguchi, PT, JAPAN Yasuhito Tanaka, Prof., JAPAN
Robotic-Assisted Total Knee Arthroplasty Improves Accuracy and Reproducibility Compared to Manual Instrumentation or Navigation. ePoster Presentation Yoan Bourgeault-Gagnon, MD, FRCSC, CANADA Lucy J. Salmon, PhD, AUSTRALIA Matt Lyons, FRACS, AUSTRALIA
Lateral Laxity is Related to the Postoperative Kinematics and Knee Symptoms After Total Knee Arthroplasty Using Medial Stabilizing Technique with a Navigation System ePoster Presentation Takahiro Tsushima, MD, PhD, JAPAN Eiji Sasaki, MD, PhD, JAPAN Kazuki Oishi, MD, JAPAN Yukiko Sakamoto, MD, PhD, JAPAN Yuka Kimura, MD, PhD, JAPAN Eiichi Tsuda, Prof., JAPAN Yasuyuki Ishibashi, MD, JAPAN
A Novel Knee Intra-Operative Classification Of Osteo-Arthritis (KICO) ePoster Presentation Geoffrey Murphy, MD, AUSTRALIA Simon Luc Edmond Walgrave, MD, BELGIUM Alexander S. Nicholls, MSc, FRACS, AUSTRALIA Myles R. J. Coolican, FRACS, AUSTRALIA David A. Parker, MBBS, BMedSc, FRACS, AUSTRALIA Brett A. Fritsch, MBBS BSc(Med), FRACS, FAOrthA, AUSTRALIA
Predictors of High Oxford Knee Scores at 1 year Following TKR - Analysis of 4126 knees at a Single Centre ePoster Presentation Payam Tarassoli, MBChB, BSc, DipSEM, MD, FRCS, AUSTRALIA Yoong Lim, BEng, PhD, AUSTRALIA David A. Parker, MBBS, BMedSc, FRACS, AUSTRALIA
The Mind Matters: Psychological Factors Influence Subjective Outcomes Following Unicompartmental Knee Arthroplasty - A Prospective Study ePoster Presentation Gaby Victoria Ten Noever De Brauw, NETHERLANDS Margot B. Aalders, MD, NETHERLANDS Hendrik Aernout Zuiderbaan, MD PhD, NETHERLANDS Lucien C.M. Keijser, MD PhD, NETHERLANDS Joyce L. Benner, PhD, NETHERLANDS
Local Soft Tissue Thickness in Unicompartimental Knee Arthroplasty: Strong Inter-Parameter Correlation, Moderate Correlation with BMI, and no Impact on Implant Positioning ePoster Presentation Lorenz Pichler, MD, AUSTRIA Moses Kamal Dieter El Kayali, MD, GERMANY Rosa Berndt, MD, GERMANY Carsten Perka, MD, PhD, GERMANY Clemens Gwinner, MD, GERMANY Danko Dan Milinkovic, MD, GERMANY
Anxiety And Depression Prior To Total Knee Arthroplasty Are Associated With Worse Pain And Subjective Function: A Prospective Comparative Study ePoster Presentation Margot B. Aalders, MD, NETHERLANDS Jelle P. van der List, MD, PhD, NETHERLANDS Dirk Jan Hofsteee, NETHERLANDS Lucien C.M. Keijser, MD PhD, NETHERLANDS Joyce L. Benner, PhD, NETHERLANDS
Use of Patient-Specific 3D-Printed Intraoperative Spacers in Complex Revision Total Knee Arthroplasty. Surgical Technique and Preliminary Results. ePoster Presentation Giulio Vittone, MD, ITALY Marcello Motta, MD, ITALY Marco Adriani, MD, ITALY Alberto Guizzi, ITALY Alessandro Colosio, MD, ITALY Giuseppe Milano, Prof., ITALY
EARLY LOOSENING OF THE FEMORAL STEM IN CEMENTED SEGMENTAL PROSTHESES WITH DISTAL FEMUR REPLACEMENT ePoster Presentation Clara Chimeno Pigrau, MD, SPAIN Marta Sabater Martos, Md, SPAIN Mariano Balaguer-Castro, MD, MSc, PhD, SPAIN Marc Ferrer Banús, MD, SPAIN Montserrat Monfort Mira, MD, SPAIN Dragos Popescu, MD, PhD, SPAIN Salvi Prat, SPAIN Joan Sugrañes, SPAIN Juan C. Martinez-Pastor, MD, SPAIN
The Femoral Cuts Correlation Between Robotic And Conventional Surgery In Total Knee Arthroplasty: A Cadaveric Study ePoster Presentation Berta Gasol Cudos, MD, SPAIN Juan Ignacio Erquicia, MD, PhD, SPAIN Eric Camprubí, MD, SPAIN Albert Pons Riverola, MD, SPAIN Angela Zumel, PhD, SPAIN Joan Leal-Blanquet, MD, PhD, SPAIN
Is Bi-Cruciate Stabilized Total Knee Arthroplasty Better Than Conventional Knee Arthroplasty In Knee Biomechanics During Gait? ePoster Presentation Kengo Harato, MD, PhD, JAPAN Kohei Nishizawa, PhD, JAPAN Shu Kobayashi, MD, PhD, JAPAN Kazuya Kaneda, MD, PhD, JAPAN Tatsuaki Matsumoto, MD, PhD, JAPAN Takeo Nagura, MD, JAPAN
Clinical and Radiological Comparison of Unicompartmental vs Patellofemoral vs Total Knee Arthroplasty ePoster Presentation Kewin Sony, MBBS, MRes, UNITED KINGDOM Oday Al-Dadah, MBChB, MD, FRCS (Tr & Orth), UNITED KINGDOM
Differences In Coronal Plane Alignment Of The Knee (CPAK) Measured On Long-Leg Radiographs Compared To Computed Tomography For The Patients Undergoing Total Knee Arthroplasty ePoster Presentation Kohei Kawaguchi, MD, PhD, JAPAN Mei Lin Tay, PhD, NEW ZEALAND Bill Farrington, FRCS, NEW ZEALAND Rupert S Van Rooyen, MBChB, FRACS, NEW ZEALAND Matthew Walker, MBChB, FRACS, NEW ZEALAND Ali Bayan, MBChB, FRACS, NEW ZEALAND Simon W. Young, MD, FRACS, NEW ZEALAND
Forgotten Joint Score : Role in Identifying Patients Unlikely To Improve Following Total Knee Arthroplasty ePoster Presentation Adit Rajesh Maniar, MBBS, MS Orthopaedics, DNB Orthopaedics, INDIA Rajesh Maniar, INDIA Ishan Khanna, MBBS, MS, INDIA Pranav Shere, MS,DNB , INDIA Anish Nandkumar Tawde, M. S. Orthopaedics , INDIA Muhammad Naqvi, MBBS, MS, DNB, FNB, MRCSEd, INDIA
Does Robotic Assistance In Total Knee Arthroplasty Improve Preoperative Planning And Intraoperative Decision-Making? ePoster Presentation David H. Figueroa, MD, CHILE Waldo Gonzalez Duque, MD, CHILE Rafael Calvo, MD, CHILE Francisco Figueroa, MD, CHILE
Impact of Unilateral and Bilateral Total Knee Arthroplasty for Bilateral Osteoarthritis on Postoperative Fractures Risk ePoster Presentation Hiroshi Fujii, MD, PhD, JAPAN
Single-Shot Femoral Nerve Block Versus Local Infiltration Analgesia For Patients Undergoing Total Knee Arthroplasty: A Systematic Review And Meta-Analysis ePoster Presentation André Richard Da Silva Oliveira Filho, Student, BRAZIL Elcio Machinski, md, BRAZIL Vinícius Furtado, Student, BRAZIL Rodrigo Conde, MS, ARGENTINA Bruno Butturi Varone, MD, BRAZIL Riccardo Gomes Gobbi, MD, PhD, BRAZIL Camilo P. Helito, MD, PhD, Prof, BRAZIL Daniel Leal, MD, BRAZIL
Investigation Of Factors Predicting Postoperative Alignment In Unicompartmental Knee Arthroplasty For Knees With Over 10 Degrees Of Varus Deformity. ePoster Presentation Masaki Mori, MD, PhD, JAPAN Naoto Date, MD, JAPAN Kengo Kaji, MD, JAPAN Masakazu Ishikawa, MD, PhD, JAPAN
Novel Algorithm for Gap Balancing and Bone Cuts in Robotic Total Knee Replacements Significantly Improves Accuracy and Surgical Duration ePoster Presentation Glen Liau , MBBS, MRCS, MMed, FRCS, FAMS, MBA, SINGAPORE Matthew Song Peng Ng, MBBS, SINGAPORE Ryan Wai Keong Loke, MBBS candidate, SINGAPORE
Influence of Femorotibial Posterior Overhang and Posterior Tibial Slope on Patellar Changes After TKA ePoster Presentation Shunsuke Utsumi, MD, JAPAN Takashi Aki, PhD, JAPAN Masayuki Kamimura, JAPAN Kento Harada, MD, JAPAN Toshimi Aizawa, JAPAN
Gait Analysis Focusing On The Relationship Between Knee Biomechanics And Patient Outcome In Unilateral Total Knee Arthroplasty And Nonoperative Residual Osteoarthritis Knee ePoster Presentation Shinichi Kuriyama, MD, PhD, JAPAN Sayako Sakai, MD, JAPAN Yugo Morita, MD, PhD, JAPAN Kohei Nishitani, MD, PhD, JAPAN Shinichiro Nakamura, MD, PhD, JAPAN Shuichi Matsuda, MD, PhD, JAPAN
Impact of Preoperative Limb Alignment and Deformity on Postoperative Limb Alignment in Unicompartmental Knee Arthroplasty ePoster Presentation Takashi Ishitani, MD, JAPAN Shuhei Otsuki, MD, JAPAN Yoshinori Okamoto, MD, PhD, JAPAN
Catastrophic Full Thickness Wear In Oxinium Knee Implants: A Case Report And Analysis Of Failure Mechanisms ePoster Presentation Naman Wahal, MBBS, MS Orthopaedics, INDIA RAJESH MALHOTRA, MS Orthopaedics, FIMSA, FRCS, FACS, INDIA
Soft Tissue Balancing In Robotic-Assisted Total Knee Arthroplasty ePoster Presentation Tomoya Takasago, MD, PhD, JAPAN Katsutoshi Miyatake, MD, PhD, JAPAN Akihiro Nagamachi, MD, PhD, JAPAN
Changes In Tibial Insert Design Can Alter Knee Kinematics And Tibiofemoral Stress Distributions In Total Knee Arthroplasty ePoster Presentation Shinichi Kuriyama, MD, PhD, JAPAN Sayako Sakai, MD, JAPAN Yugo Morita, MD, PhD, JAPAN Kohei Nishitani, MD, PhD, JAPAN Shinichiro Nakamura, MD, PhD, JAPAN Shuichi Matsuda, MD, PhD, JAPAN
Early Clinical Outcome In Inverse Kinematic Alignment For Total Knee Arthroplasty Using A Robotic Assisted System: Two Years Follow-Up ePoster Presentation Federica Manca, MD, ITALY Leo Massari, Prof., ITALY Alberto Belluati, MD, ITALY Andrea Colombelli, MD, ITALY
Anatomical investigation of the popliteal artery in unicompartmental knee arthroplasty cases ePoster Presentation Naoto Date, MD, JAPAN Masaki Mori, MD, PhD, JAPAN Kengo Kaji, MD, JAPAN Masakazu Ishikawa, MD, PhD, JAPAN
An Extended-Release Sebacoyl Dinalbuphine Ester For Perioperative Pain Management In Improving Enhanced Recovery After Surgery In Total Knee Arthroplasty ePoster Presentation Jia-Lin Wu, MD, MS, TAIWAN Ching Lu, MD, TAIWAN
Changing amount of posterior tibial slope during unicompartmental knee arthroplasty does not affect short-term postoperative patients reported outcome measurement ePoster Presentation Ryo Tomita, MD, JAPAN Eiji Sasaki, MD, PhD, JAPAN Hikaru Kristi Ishibashi, MD, JAPAN Hitoshi Kudo, PhD, JAPAN Hironori Otsuka, MD, JAPAN Takahiro Tsushima, MD, PhD, JAPAN Yukiko Sakamoto, MD, PhD, JAPAN Yuka Kimura, MD, PhD, JAPAN Yasuyuki Ishibashi, MD, JAPAN
The Impact Of Aging On Recovery And Satisfaction In Knee Replacement Patients ePoster Presentation Tess L.Y Tsoi , MBChB, HONG KONG Harbeer Ahedi, PhD Biomedical Sciences, AUSTRALIA David A. Parker, MBBS, BMedSc, FRACS, AUSTRALIA
Cementless Total Knee Arthroplasty is Performed in Younger Patients ePoster Presentation Logan Finger, MD, UNITED STATES Nicole Don, MA, UNITED STATES Noah Feder, BA, UNITED STATES Kenneth Urish, MD, PhD Michael O'Malley, MD, UNITED STATES Brian Klatt, MD, UNITED STATES Johannes F. Plate, MD, PhD, UNITED STATES
Tourniquet use Does not Affect Bleeding and Surgical Time in Robotic Assisted Total Knee Arthroplasty ePoster Presentation João P.F. Guerreiro, MD, PhD, BRAZIL JOAO BALAN, MD, BRAZIL MARSAL VILHENA, MD, BRAZIL SERGIO MERÇON, MD, BRAZIL Paulo Roberto Bignardi, PhD, BRAZIL Marcus Vinicius Danieli, MD, PhD, BRAZIL
Investigating Patient And Surgical Factors Affecting Same Day Discharge After Unicompartmental Knee Replacement ePoster Presentation Suleyman Ulla, MBChB, UNITED KINGDOM Patrick Richard Michael Nicholas, MBChB, MRCS(Glasg), UNITED KINGDOM Stuart Wilson Bell, MBChB MRCP FRCS (Orth), UNITED KINGDOM
Comparison Of Outcomes Of Revision Uka To Tka And Primary Tkas -A Propensity Matched Study. ePoster Presentation Myles R. J. Coolican, FRACS, AUSTRALIA Harbeer Ahedi, PhD Biomedical Sciences, AUSTRALIA
Short-term Results and Learning Curve of TKA with Robotic Arm ePoster Presentation Masayoshi Okuda, MD, PhD, JAPAN Yuki Kawaguchi, PT, JAPAN Shuhei Sugioka, MD, JAPAN Yusuke Inagaki, MD, PhD, JAPAN Yasuhito Tanaka, Prof., JAPAN
Knees With Lateral Compartment Osteoarthritis Show A Substantial Variability In Functional Knee Phenotypes With Gender-Specific And Age-Related Differences: Phenotypic Analysis Of 305 Knees ePoster Presentation Gaby Victoria Ten Noever De Brauw, NETHERLANDS Tarik Bayoumi, MD, NETHERLANDS Lindsey Ruderman, BA, UNITED STATES Gino M. M. J. Kerkhoffs, MD, PhD, Prof., NETHERLANDS Hendrik Aernout Zuiderbaan, MD PhD, NETHERLANDS Andrew D. Pearle, MD, UNITED STATES
Changes In Foot Pressure Among Patients With Varus Knee Osteoarthritis Undergoing Bilateral Simultaneous Total Knee Arthroplasty – A Prospective Observational Pedobarographic Assessment ePoster Presentation Roop Bhushan Kalia, M.S (Orthopaedics), INDIA Divyansh Sharma, MBBS,M.S (Orthopaedics), INDIA Pradeep Kumar Meena, MBBS,M.S(Orthopaedics), INDIA Raj Kumar Yadav, MBBS,M.D, INDIA Ankit Gaurav, MS ORTHOPAEDICS, INDIA

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Acute Postoperative Pain Is An Independent Risk Factor Associated With Chronic Postoperative Pain After Total Knee Arthroplasty

Acute Postoperative Pain Is An Independent Risk Factor Associated With Chronic Postoperative Pain After Total Knee Arthroplasty

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Acute Postoperative Pain Is An Independent Risk Factor Associated With Chronic Postoperative Pain After Total Knee Arthroplasty

Acute Postoperative Pain Is An Independent Risk Factor Associated With Chronic Postoperative Pain After Total Knee Arthroplasty

Purpose

Methods

Results

Conclusion