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Predictors of The Ten-Year Patient-Reported Outcome Measures After Collagen Meniscus Implant (CMI) For Partial Meniscus Deficiency

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Predictors of The Ten-Year Patient-Reported Outcome Measures After Collagen Meniscus Implant (CMI) For Partial Meniscus Deficiency

Alberto Grassi, PhD, ITALY Gian Andrea Lucidi, MD, ITALY Piero Agostinone, MD, ITALY Stefano Di Paolo, Eng, ITALY Giacomo Dal Fabbro, ITALY Nicola Pizza, MD, ITALY Marianna Viotto, ITALY Luca Ambrosini, MD, ITALY Stefano Zaffagnini, MD, Prof., ITALY

IRCCS Rizzoli Orthopaedic Institute, Bologna, ITALY

2023 Congress ePoster Presentation 2023 Congress Not yet rated

Anatomic Location

Knee

Anatomic Structure

Meniscus Medial Lateral

Diagnosis / Condition

Dislocation

Treatment / Technique

Implant Arthroscopy

Diagnosis Method

MRI

Summary: CMI provided satisfactory results in terms of function, symptoms, sports and quality of life after more than 10 years of follow-up. Cartilage status and time from meniscectomy impact negatively on the outcomes, while an age >45 years was associated with less pain.

Background

Collagen Meniscus Implant (CMI) is considered an effective procedure for reducing knee pain and improving knee function after previous meniscectomy. Nevertheless, the current knowledge regarding the clinical results of CMI are limited to small case series at short- to mid-term follow-up studies. The goal of the present study was to evaluate clinical outcomes, reoperations, and failures of CMI at a minimum 10 years of follow-up.
Study design: Case series; Level of evidence, 4.

Methods

Consecutive patients who underwernt CMI at a single institution were screened for elegibility. Inclusion criteria for the present study were (1) Medial or Lateral CMI, (2) Isolated or combined procedure with ACL reconstruction, knee osteotomy or cartilage treatment, (3) follow-up between 10 and 15 years.
Demographics and surgical details were obtained via chart review. Patients were asked if they were satisfied with the procedure and were evaluated with the Lysholm score, Knee injury and Osteoarthritis Outcome Score (KOOS), visual analog scale (VAS) for pain, and Tegner score at the final follow-up. Survival analysis was performed with Kaplan-Meier curve, and clinical scores were analyzed based on the Patient Acceptable Symptom State (PASS).
Results:A total of 92 patients (mean age, 42.8 years) were included in the analysis.
A significant improvement in all the clinical scores was reported between the preoperative evaluation and the last follow-up. A chondropaty with outerbridge grade =III was associated with significantly overall lower clinical score, while a timing from meniscectomy to CMI implant to =5 years determined more pain at rest and lower score in the KOOS quality of life.
Overall, 25% of patients did not achieved the PASS for Lysholm score and a percentage variable from 19% (KOOS Pain) and 40% (KOOS Symptoms) did not achieved the PASS in the KOOS subscales. Chondropaty with outerbridge grade =III was associated with an higher Risk of not achieving the PASS in all the KOOS subscales, while an age at surgery =45 years was resulted in a lower risk of not achieving PASS in the pain subscale.
At the last follow-up 63% of patients returned to sport practice after CMI implantation, with 41% at the same or higher level. Finally, 80% of the patients were satisfied with the procedure.

Conclusion

CMI provided satisfactory results in terms of function, symptoms, sports and quality of life in 60% to 80% of the patients after more than 10 years of follow-up with clinical scores still higher compared to the preoperative evaluation. The cartilage status and the time from meniscectomy have shown to impact negatively on the outcomes, while an age >45 years was associated with less pain.

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Cross-Sectional Effects of Isolated Meniscal Tears on In Vivo Biomechanics of the Knee: A Systematic Review Of Motion Analysis Studies ePoster Presentation Enzo Salviato Mameri, MD, MSc, BRAZIL Garrett Jackson, MD, UNITED STATES Harkirat Jawanda, BS, UNITED STATES Jonathan A Gustafson, PhD, UNITED STATES Leonardo Metsavaht, MD PhD, BRAZIL Jorge Chahla, MD, PhD, UNITED STATES
A New Arthroscopic Pull-In All-Suture Anchor Meniscus Root Tear Repair Shows Comparable Biomechanical Properties as Conventional Trans-Osseous Pull-Out and Anchor Repair ePoster Presentation Thorben Briese, MD, GERMANY Amaris Kieninger, MD, GERMANY Elmar Herbst, MD, PhD, GERMANY Johannes Glasbrenner, MD, GERMANY Christian Peez, MD, GERMANY Adrian Deichsel, MD, GERMANY Maurice Balke, MD, GERMANY Jens Wermers, Prof., GERMANY Matthias Klimek, M. Sc., GERMANY Michael J. Raschke, MD, Prof., GERMANY Christoph Kittl, MD, MD(res), GERMANY
Arthroscopic Treatment of Meniscal Cysts and Clinical Follow Up ePoster Presentation Sang Hak Lee, MD, PhD, KOREA, REPUBLIC OF Tae Wook Kim, MD, KOREA, REPUBLIC OF Bo Seung Bae, MD, KOREA, REPUBLIC OF Jun Bum Park, MD, KOREA, REPUBLIC OF Min-Gyu Kim, MD, KOREA, REPUBLIC OF
Comparison Of Resultant Force Through The Repaired Lateral Meniscus With Between Inside-Out And All-Inside-Suture Techniques ePoster Presentation Takehito Hirose, MD, PhD, JAPAN Tatsuo Mae, MD, PhD, JAPAN Satoshi Yamakawa, PhD, JAPAN Issei Ogasawara, PhD, JAPAN Shoji Konda, PhD, JAPAN Yasuhiro Take, MD, PhD, JAPAN Ken Nakata, MD, PhD, JAPAN

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Predictors of The Ten-Year Patient-Reported Outcome Measures After Collagen Meniscus Implant (CMI) For Partial Meniscus Deficiency

Predictors of The Ten-Year Patient-Reported Outcome Measures After Collagen Meniscus Implant (CMI) For Partial Meniscus Deficiency

Background

Methods

Conclusion

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Predictors of The Ten-Year Patient-Reported Outcome Measures After Collagen Meniscus Implant (CMI) For Partial Meniscus Deficiency

Predictors of The Ten-Year Patient-Reported Outcome Measures After Collagen Meniscus Implant (CMI) For Partial Meniscus Deficiency

Background

Methods

Conclusion

More 2023 ISAKOS Congress Content