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Minimum 10-Year Clinical Outcome Of Lateral Collagen Meniscus Implants (Cmi) For The Replacement Of Partial Lateral Meniscus Defects.

2021 Congress Paper Abstracts

Minimum 10-Year Clinical Outcome Of Lateral Collagen Meniscus Implants (Cmi) For The Replacement Of Partial Lateral Meniscus Defects.

Alberto Grassi, MD, ITALY Gian Andrea Lucidi, MD, ITALY Giuseppe Filardo, MD, PhD, Prof., ITALY Paolo Bulgheroni, MD, ITALY Erica Bulgheroni, MD, ITALY Luca Macchiarola, MD, ITALY Piero Agostinone, MD, ITALY Giacomo Dal Fabbro, ITALY Stefano Zaffagnini, MD, Prof., ITALY

Istituto Ortopedico Rizzoli, Bologna, Bologna, ITALY

2021 Congress   ePoster Presentation     Not yet rated


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Summary: Lateral CMi provide stable results over time even at a long term follow-up in the treatment of partial meniscus defectes


Collagen Meniscus Implant (CMI) is a biologic scaffold aimed at replacing partial meniscal defects. The short-term results of lateral meniscus replacement are known; however, the long-term results have never been investigated.


The aim of this study was to document the long-term clinical outcome and failures of lateral CMI implantation for partial lateral meniscus defect at a minimum 10-year follow-up. Material and methods: Twenty-four consecutive patients underwent lateral CMI implantation for partial lateral meniscal defects between April 2006 and September 2009 and were included in the study. Lysholm score, KOOS score, VAS for pain, the Tegner activity level, and the EQ-5D score were obtained. Data regarding complications and failures were also documented.


Nineteen patients (16 males, 3 females) with a mean age at surgery of 37.1 ± 12.6 years were included in the final analysis at an average follow-up of 12.4 ± 1.5 years (range 10 – 14). Five failures were reported (26%): 1 CMI removal due to implant breakage and 4 joint replacements (2 UKA and 2 TKA). The implant overall survival was 96% at 2 years, 85% at 5 years 85% at 10 years, 77% at 12 years, and 64% at 14 years. The Lysholm score at the final follow-up was 82 ± 14, with 5/14 (36%) rated as “Excellent”, 6/14 (43%) as “Good” and 3/14 (21%) as “Fair””. VAS for pain was 3.1 ± 3.1, with only 3/19 patients (16%) reporting to be pain-free; the Tegner Activity score was 3 (IQR 2-5). In summary, all the average clinical scores decreased from the 2-year follow-up.
However, their values remained significantly higher respect to the pre-operative status, except for the Tegner score. Moreover, 78% reported being willing to undergo the same procedure.


Lateral CMI for partial lateral meniscus defects provided good long-term results, with a 10-yearsurvival rate of 85% and a 14-year survival rate of 64%. At the final follow-up, 58% of the patients were considered “good” or “excellent” according to the Lysholm score. However, a general decrease of PROMs was present from short to long-term follow-up

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