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Substantial Clinical Benefit In The Patient Reported Outcomes Following Primary Anterior Cruciate Ligament Reconstruction

Substantial Clinical Benefit In The Patient Reported Outcomes Following Primary Anterior Cruciate Ligament Reconstruction

Youngsik Jeon, MD, KOREA, REPUBLIC OF Jihoon Bae, MD, PhD, KOREA, REPUBLIC OF Tae Jin Lee, MD, KOREA, REPUBLIC OF Taejin Kim, MD, KOREA, REPUBLIC OF

KOREA UNIVERSITY GURO HOSPITAL, SEOUL, GURO-GU, KOREA, REPUBLIC OF


2021 Congress   ePoster Presentation     Not yet rated

 

Anatomic Location

Anatomic Structure

Diagnosis / Condition

Treatment / Technique

Ligaments

ACL

Sports Medicine

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Summary: Postoperative patient-reported outcomes (PROs) including the Lysholm score, IKDC-SKF, and ACL-RSI scale showed excellent reliability about predicting the substantial clinical benefit (SCB) after the anterior cruciate ligament reconstruction in general population. The age at the time of surgery and thigh muscle strength influenced reaching the SCB for each PRO.


Background

In patients with anterior cruciate ligament reconstruction (ACLR), little is known about the threshold of patient-reported outcomes (PROs) at which patients perceive to have attained a substantial clinical benefit (SCB). No previous study has evaluated the SCB of ACLR in terms of daily activities in general population.

Hypothesis/Purpose: PROs commonly used in ACLR would have acceptable reliability in predicting SCB, and previously identified factors, such as demographic factors and isokinetic tests, would be able to predict reaching the SCB value of each PRO.

Study Design: Case Series; Level of Evidence: 4.

Methods

The Lysholm score, International Knee Documentation Committee Subjective Knee Evaluation Form (IKDC-SKF), Tegner activity scale, and the ACL–Return to Sport after Injury (ACL-RSI) scale were examined pre- and postoperatively in 76 patients who underwent ACLR. Patients responded to two independent anchor questions about daily discomfort and functional recovery at the 12-month follow-up visit. Receiver operating characteristic (ROC) curve was used to differentiate between patients who responded being “none” or “mild” difficulty with use of a question derived from the Knee injury and Osteoarthritis Outcome Score (KOOS) subscale and between those who answered with a score of = 8 or < 8 out of 10 with use of non-validated but more injury-specific functional question. For each SCB measure, two response parameters were used : raw score at postoperative one-year, net change. Multivariable regression analyses were performed to determine factors affecting the SCB.

Results

The raw postoperative scores corresponding to the SCB for the Lysholm, IKDC-SKF, Tegner, and ACL-RSI scale were 88.0, 85.1, 6.5, and 64.2 for the first anchor question and 84.5, 77.7, 5.5, and 57.1 for the second anchor question, respectively. The AUC values obtained from analysis of the raw postoperative PROs, unlike the net score changes, were all statistically significant (P < .05), with acceptable to excellent reliability. Younger age and greater muscle strength were predictive of SCB achievement in all PROs.

Conclusion

The postoperative Lysholm, IKDC-SKF, and ACL-RSI scale scores showed excellent reliability in predicting the SCB after ACLR in the general population. The age at surgery and thigh muscle strength influenced the SCB for each PRO.

Key Terms: anterior cruciate ligament reconstruction; general population; patient-reported outcome; significant clinical benefit